Breast cancer is the second most common cancer among women in the United States. Studies are providing a better understanding of the underlying biology of breast cancer and identifying opportunities for treatments. Researchers at Georgetown Lombardi Comprehensive Cancer Center conducted one such investigation. They analyzed expanded epithelial cells from women with breast cancer who had chemotherapy before their surgery and found
Earlier this week the US Food and Drug Administration (FDA) Approved a Biologics License Application (BLA) for bevacizumab-maly, a biosimilar referencing Avastin (bevacizumab). This is the third biosimilar of bevacizumab approved in the US. A biosimilar is a medication that is almost identical to another medication. The approval of biosimilar products is regulated by the 2010 Biologics Price Competition and Innovation
Your health risks are often dependent upon your genetics. Assessing a single DNA difference that has a small effect on risk may not be clinically useful. However, when hundreds or thousands of these small risks are added up into a single score, often called a polygenic risk score (PRS), they might offer clinically meaningful information about a person’s disease risk.
The US Department of Agriculture reports that avian flu has now spread to 30 states. Avian influenza (AI) is caused by an influenza type A virus which is classified by a combination of two groups of proteins: hemagglutinin or “H” proteins, of which there are 16 (H1–H16), and neuraminidase or “N” proteins, of which there are 9 (N1–N9). AI viruses
The National Institute on Aging reports that depression is a common problem among older adults. Social Isolation brought on by the COVID -19 pandemic has exacerbated the problem. However, depression is not a normal part of aging and is treatable. New research suggests that improving cardiovascular (CV) health may also help in preventing the onset of depression in the elderly.
The CDC estimates that as many as 6.5 million Americans are living with Alzheimer’s disease. This number is projected to nearly triple to 14 million people by the year 2060. Alzheimer’s disease is the most common form of dementia that results in memory loss and cognitive impairment in the US. A new study by a team of researchers from the
Clinical trials are necessary to help identify safe and effective methods for preventing, diagnosing, and treating diseases. However, a systematic review published in the journal Med finds that clinical trial protocols often do not reference accessible, relevant trials and do not document systematic searches for relevant clinical trials. Subsequently, ethics review committees receive an incomplete picture of the research landscape
The Centers for Disease Control and Preventions estimate that 151,726 nursing home residents and staff have died from Covid-19 since the beginning of the pandemic. The effect of the pandemic on staffing and providing high-quality nursing home care has been devastating. A report by the National Academies of Sciences, Engineering, and Medicine found that wide-ranging systemic changes are needed to
The Stress in America™ 2021 Survey conducted by the Harris Poll on behalf of the American Psychological Association found that 32% of Americans were so stressed out about the coronavirus pandemic that they were struggling to make even basic decisions such as what to wear, or what to eat. The reported stress varied by age group. The data showed that
Colorectal cancer is the third most common cancer worldwide. An estimated 106,180 new cases of colon cancer and 44,850 new cases of rectal cancer will be diagnosed in the US in 2022. Many of these patients will develop unresectable colorectal cancer liver metastases (CRLMs). A March 2022 study is the first in North America to demonstrate that a living-donor liver